Synthesis of DL-Heptadecane-1,14-diol.

Synthesis and antibacterial activity of DL-threo-1-(1-methylsulfonylpyrrole-3-yl)-2-difluoroacetamidopropane-1,3-diol.

The three-stage synthesis of a pyrrole analogue of chloramphenicol (5) was described. It is inactive.

Synthesis and Biological Evaluation of Chlorinated Analogs of Leukotoxin Diol.

This study documents that chlorinated analogs of leukotoxin diol 1, in which the vic-diol has been replaced with vic-chlorides (2), induce caspase 3 activity and apoptosis on HepG2 cells in a dose-dependent manner in analogy to the parent diol. This suggests that chlorides may substitute for hydroxyls in certain lipids as bioisosteres in defined biological settings.

Synthesis and evaluation of poly(diol citrate) biodegradable elastomers.

Herein, we report the synthesis and evaluation of a novel family of biodegradable and elastomeric polyesters, poly(diol citrates). Poly(diol citrates) were synthesized by reacting citric acid with various diols to form a covalent cross-linked network via a polycondensation reaction without using exogenous catalysts. The tensile strength of poly(diol citrates) were as high as 11.15+/-2.62 MPa an...

Total synthesis of enokipodins A-D and cuparene-1,4-diol

Convenient method for synthesis of a carbon-14 analogue of DL-Phenyl alanine

DL-Phenyl alanine labeled with carbon-14 in the α-position has been synthesized from ethyl[2-14C] acetate as part of a 6-step sequence.